Catfish One at 444 Hwy 51 S in Brookhaven, Mississippi is a beloved local seafood spot known for its crispy Southern-fried catfish fillets, shrimp baskets, stuffed crab, and generous combo platters. Open Thursday through Saturday, the restaurant draws a loyal crowd with its affordable prices, friendly service, and classic comfort-food sides like hushpuppies, coleslaw, and fries.
Signature items
The restaurant's signature dish
Prices sourced from publicly available listings. Contact restaurant to confirm current pricing.
| Item | Category | Price |
|---|---|---|
| Stuffed Crab | Seafood | $1.99 ea |
| Large Fish | Catfish | $9.99 |
| Seafood Platter | Seafood | $15.99 |
| Shrimp Basket | Shrimp | Unconfirmed |
| Catfish & Shrimp Combo | Combo | Unconfirmed |
| Chicken Tenders | Chicken | Unconfirmed |
Catfish One's documented prices stack up well against regional seafood restaurants in the South.
| Category | Catfish One | Pappadeaux Seafood | Bonefish Grill | Local Seafood Average |
|---|---|---|---|---|
| Fish plate / entree | $9.99 | $18–$24 | $16–$22 | $12–$16 |
| Seafood platter | $15.99 | $28–$36 | $24–$30 | $18–$25 |
| Shrimp basket | Unconfirmed | $14–$18 | $15–$20 | $10–$14 |
| Stuffed/specialty crab | $1.99 ea | $12–$16 | $13–$18 | $6–$12 |
Catfish One has been a fixture of the Brookhaven, Mississippi dining scene for years, serving up freshly fried catfish and Southern-style seafood to locals and travelers passing through on US-51. Situated at 444 Hwy 51 S, the restaurant operates with a focused, no-frills approach — open Thursday through Saturday from 3 PM to 8 PM — and has built a loyal following through consistent quality and honest value.
The restaurant's identity is rooted in Mississippi's deep tradition of catfish culture. The Mississippi Delta and surrounding areas have long been among the nation's top catfish-producing regions, and spots like Catfish One keep that culinary tradition alive with straightforward preparations that let the fish speak for itself. Crispy fried catfish fillets served alongside hushpuppies, coleslaw, and fries represent the platonic ideal of a Southern fish house, and regulars return week after week for exactly that experience.
Beyond catfish, the menu rounds out with shrimp baskets, stuffed crab, boiled shrimp, oysters, and a full seafood platter for those seeking a more expansive meal. Chicken tenders and classic Southern sides round out the offerings. Catfish One accepts credit cards and offers both dine-in and takeout service, making it a convenient stop for anyone hungry in Lincoln County.
Confirm today's menu, hours, and prices by calling the restaurant directly or stopping in Thursday through Saturday from 3–8 PM.
Get directions to Catfish OneCatfish One is located at 444 Hwy 51 S, Brookhaven, MS 39601. The restaurant sits along US-51, making it accessible to both locals and travelers passing through Lincoln County.
Catfish One is open Thursday through Saturday from 3:00 PM to 8:00 PM. The restaurant is closed Sunday through Wednesday. Hours may vary on holidays, so it's worth calling ahead at (601) 833-3044.
Catfish One is best known for its Southern-fried catfish fillets — crispy, fresh-cooked, and not greasy. Regulars also love the stuffed crab, shrimp basket, and the full seafood platter for a generous all-in-one meal.
Yes, Catfish One offers takeout in addition to dine-in service. You can call ahead at (601) 833-3044 to place a takeout order and pick it up during operating hours.
Catfish One is considered affordable, with an estimated price range of $10–$25 per person. A large fish plate has been documented at $9.99 and the seafood platter at $15.99, though prices may have changed. Call to confirm current pricing.
Yes, Catfish One accepts credit card payments. The restaurant does not require cash-only payment, making it convenient for most diners.
Classic Southern sides at Catfish One include hushpuppies, coleslaw, French fries, and fried pickles. Most entrees come paired with sides — check with the restaurant on what's included with each plate.
Yes. In addition to catfish, Catfish One serves shrimp baskets, boiled shrimp, oysters, stuffed crab, a full seafood platter, and chicken tenders. There's something for most tastes, even for those who aren't catfish fans.
Catfish One is a casual, welcoming spot well-suited for families. The affordable prices, generous portions, and approachable Southern menu make it a comfortable choice for groups of all ages visiting Brookhaven, MS.